LONDON - FA Cup holders Chelsea could face Premier League leaders Manchester United at Old Trafford in the quarter-finals if both win fifth-round ties.
United must beat Reading in their last-16 meeting tonight while Chelsea, who crushed Brentford 4-0 in a fourth-round replay on Sunday, have to get past Championship Middlesbrough who they meet at the Riverside on February 27.
United last reached the FA Cup final in 2007 which they lost 1-0 to Chelsea at Wembley with Didier Drogba scoring the winner late in extra time.
Manchester City, the 2011 winners, were drawn at home to second-tier Barnsley.
Sunday's last-eight draw created another potential all top-flight encounter with Everton hosting Wigan if David Moyes's side can get past League Two Oldham Athletic in a replay at Goodison Park.
Oldham scored a stoppage-time equaliser to hold Everton to a 2-2 draw on Saturday.
Blackburn Rovers were rewarded for a shock 1-0 fifth-round win at Arsenal with another trip to the capital, this time to face fellow Championship outfit Millwall, the 2004 finalists.
Meanwhile, Manchester United are expected to ring the changes for their FA Cup fifth-round clash with Reading tonight, but manager Alex Ferguson still expects his new-look side to get through against the Premier League strugglers.
United came through their midweek Champions League last-16 1-1 draw with Real Madrid with no fresh injuries, but Ferguson still wants to utilise the strength in depth at his disposal.
"We've come through Wednesday's game without any injuries," said the Scot. "That's the best thing, apart from the result of course. I'll make some changes for Monday night, even though it's an incentive to get to the quarter-final. I don't think that's lost on any of the players.
"There's a good spirit in place and they're all contributing. Whatever side I pick we're expected to qualify. That's what happens at United. Whatever team you play you're always expected to win.
"I went to see Reading last week and they're a team who are showing plenty of fighting qualities at the moment, as you'd expect given they're down the bottom of the league.
"We'll take nothing for granted. In the FA Cup you always expect the unexpected. It happens so many times. You just hope you're not a casualty or a shock."
Midfielder Paul Scholes, who has not featured since the end of January, is still struggling with a knee injury and could be out for two weeks, the club said on their website. (Reuters)